- BLOG Bulletin of WPP’S -

Prevalence and Risk Factors for Parkinsonism by Abdul Rana MD

February 29, 2016 | Tags: Categories for this post are: Educational Material,Parkinson’s Disease

Dr. Abdul Rana MD, Neurologist from Toronto, and World-Renown Parkinsonism Education Expert, talks about the Incidence and Prevalence of Parkinsonism, as well as its Risk Factors and Presenting signs and symptoms. ... Read more

Loss of Sense of Smeall in Parkinsonism by Dr. A.Q. Rana Neurologist

February 28, 2016 | Tags: Categories for this post are: Educational Material,Parkinson’s Disease

Loss of Sense of Smell is one of the pathologic symptoms of Parkinsonism and Parkinson's Disease. It occures in younger Parkinsonism patiens, and affects men and women equally, and sometimes is accompanied by loss of taste. ... Read more

Familial Neurodegenerative Diseases causing Parkinsonism

February 26, 2016 | Tags: Categories for this post are: Parkinson’s Disease

(see section on differential diagnosis) Heterodegenerative conditions like Wilson’s disease, Huntington’s disease, Hallervorden-Spatz disease, Familial basal ganglionic calcification and Familial olivopontocerebellar atrophy may have some features similar to Parkinson’s disease. As mentioned above, Parkinson’s disease constitutes about 75-80% of cases of Parkinsonism. In the... Read more

Atypical Parkinsonism or Parkinson Plus Syndromes

February 24, 2016 | Tags: Categories for this post are: Parkinson’s Disease

These conditions have clinical features similar to Parkinson’s disease and initially may be difficult to differentiate from Parkinson’s disease solely based on the clinical examination. From the prognostic point, it is important to distinguish these conditions from classic Parkinson’s disease because the life expectancy in these conditions is shorter. In contrast to Parkinson’s disease,... Read more

What is Primary and Secondary Parkinsonism

February 22, 2016 | Tags: Categories for this post are: Parkinson’s Disease

A) Primary Parkinsonism: Primary Parkinsonism is due to classic idiopathic Parkinson’s disease and includes sporadic and familial cases. The classic idiopathic Parkinson’s disease makes up about 75-80% of cases of Parkinsonism. B) Secondary Parkinsonism: Secondary parkinsonism could be due to many known causes such as: 1. Drug induced (see section on differential diagnosis) 2.... Read more

Classification of Parkinsonism

February 19, 2016 | Tags: Categories for this post are: Parkinson’s Disease

Parkinsonism is classified into four main categories as follows. A. Primary (idiopathic) Parkinsonism 1. Parkinson’s Disease (sporadic and genetic) B. Secondary Parkinsonism (Acquired) 1. Drugs Induced: Antipsychotics such as dopamine receptors blocking drugs, antiemetics such as metoclopramide, dopamine depleting drugs like reserpine, tetrabenzine, alpha-methyl-dopa, lithium,... Read more

Does Iron supplements can exacerbate Parkinson’s disease?

February 15, 2016 | Tags: > Categories for this post are: Parkinson’s Disease

There is some suggestion that free radicals made by iron can worsen Parkinson’s disease by furthering damage to neurons. After iron is ingested, it is absorbed into the blood and bound to the protein transferrin. Transferrin travels through the blood and binds to specific receptors on certain cells—including the neurons in the substantia nigra. Once bound, the transferrin-iron complex is... Read more

Classic Idiopathic Parkinson’s Disease

January 25, 2016 | Tags: > > Categories for this post are: Parkinson’s Disease

Classic idiopathic Parkinson’s disease is a progressive condition with asymmetrical onset and is characterized by motor and non-motor symptoms. Patients with classic Parkinson’s disease may present with a variety of symptoms as discussed below. A. MOTOR SYMPTOMS OF PARKINSON’S DISEASE: 1. Bradykinesia: Bradykinesia is described by the patient as slowness of movements while performing... Read more

Protective Factors For Parkinson’s Disease

January 16, 2016 | Tags: Categories for this post are: Parkinson’s Disease

Protective factors, if present, seem to decrease the risk of developing Parkinson’s Disease. The factors studied for protective effects include smoking, nicotine, caffeine, NSAID, omega 3 fatty acids, and hormone replacement therapy. Individuals who smoke or use smokeless tobacco have reduced the risk of developing Parkinson’s disease. This may suggest that nicotine may have a... Read more

What toxins have been linked to secondary parkinsonism?

January 1, 2016 | Tags: > Categories for this post are: Parkinson’s Disease,Theories

Exposure to a number of toxins has been associated with parkinsonism, including: • Mercury- this includes usage in dental amalgams (in the past), in dental fluorescent lamps, preservative thimerosol in vaccines and thermometers. • MPTP - a compound found in animal models of Parkinson’s disease. • Rotenone - a pesticide used in making animal models of Parkinson’s disease. •... Read more

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