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What are Lewy bodies?

March 10, 2016 | Categories for this post are: Uncategorized

Lewy bodies are spherical aggregates of protein that accumulate in the dopaminergic neurons, and are almost exclusively found in Parkinson’s disease. Furthermore, immunohistochemistry has demonstrated these Lewy bodies are primarily composed of various inappropriately folded and undigested proteins including: alpha-synuclein, ubiquitin, microfilament and microtubule subunits.

Lewy bodies